GS_00GRSL2.1

Display Name: USA/GS_00GRSL2.1/2025-10-29
M. Kirby, R. Garten, T. Davis & V. Dugan

Submission details

Submission ID
PX839534.1.seg1/PX839533.1.seg2/PX839535.1.seg3/PX839536.1.seg4/PX839537.1.seg5/PX839538.1.seg6/PX839539.1.seg7/PX839540.1.seg8
Submitting group
Date submitted
2026-01-09 05:08:52 UTC
Date released
2026-01-09 05:09:33 UTC

Authors

Author affiliations
Centers for Disease Control and Prevention, Influenza Division

INSDC

Bioproject accession
INSDC accession seg1
INSDC accession seg2
INSDC accession seg3
INSDC accession seg4
INSDC accession seg5
INSDC accession seg6
INSDC accession seg7
INSDC accession seg8
NCBI release date
2026-01-08

Clade

Clade HA
V1A.3a.2
Clade NA
B.8

Alignment states and QC metrics seg1

Completeness seg1
100.00%
Length seg1
2340
Total ambiguous nucs seg1
0
Total deleted nucs seg1
0
Total frame shifts seg1
0
Total inserted nucs seg1
6
Total SNPs seg1
49
Total unknown nucs seg1
0

Alignment states and QC metrics seg2

Completeness seg2
99.96%
Length seg2
2367
Total ambiguous nucs seg2
1
Total deleted nucs seg2
0
Total frame shifts seg2
0
Total inserted nucs seg2
9
Total SNPs seg2
58
Total unknown nucs seg2
0

Alignment states and QC metrics seg3

Completeness seg3
100.00%
Length seg3
2275
Total ambiguous nucs seg3
0
Total deleted nucs seg3
0
Total frame shifts seg3
0
Total inserted nucs seg3
30
Total SNPs seg3
59
Total unknown nucs seg3
0

Alignment states and QC metrics seg4

Completeness seg4
98.46%
Length seg4
1847
Total ambiguous nucs seg4
0
Total deleted nucs seg4
9
Total frame shifts seg4
0
Total inserted nucs seg4
0
Total SNPs seg4
57
Total unknown nucs seg4
0

Alignment states and QC metrics seg5

Completeness seg5
100.00%
Length seg5
1815
Total ambiguous nucs seg5
0
Total deleted nucs seg5
0
Total frame shifts seg5
0
Total inserted nucs seg5
65
Total SNPs seg5
37
Total unknown nucs seg5
0

Alignment states and QC metrics seg6

Completeness seg6
100.00%
Length seg6
1528
Total ambiguous nucs seg6
0
Total deleted nucs seg6
0
Total frame shifts seg6
0
Total inserted nucs seg6
127
Total SNPs seg6
32
Total unknown nucs seg6
0

Alignment states and QC metrics seg7

Completeness seg7
100.00%
Length seg7
1154
Total ambiguous nucs seg7
0
Total deleted nucs seg7
0
Total frame shifts seg7
0
Total inserted nucs seg7
7
Total SNPs seg7
16
Total unknown nucs seg7
0

Alignment states and QC metrics seg8

Completeness seg8
99.62%
Length seg8
1066
Total ambiguous nucs seg8
0
Total deleted nucs seg8
0
Total frame shifts seg8
0
Total inserted nucs seg8
4
Total SNPs seg8
19
Total unknown nucs seg8
0

Sample details

Collection country
USA
Collection subdivision level 1
Massachusetts
Collection date
2025-10-29
Isolate name
B/Massachusetts/49/2025

Host

Host name scientific
Homo sapiens
Host taxon id

INSDC seg4

Lineage seg4
vic

Nucleotide mutations

Mutations called relative to the CY115157.1, CY115158.1, CY115156.1, KX058884.1, CY115154.1, CY073894.1, CY115152.1 & CY115155.1 references

Substitutions

seg1

  • seg1:C113T
  • seg1:G197A
  • seg1:A200G
  • seg1:A359G
  • seg1:G383A
  • seg1:C434T
  • seg1:T522C
  • seg1:C528A
  • seg1:G593A
  • seg1:C746A
  • seg1:A827G
  • seg1:C854T
  • seg1:A950G
  • seg1:T962C
  • seg1:T968C
  • seg1:T995C
  • seg1:C1037A
  • seg1:G1064A

    • seg2

  • seg2:G12A
  • seg2:A54G
  • seg2:G81A
  • seg2:T171C
  • seg2:T174C
  • seg2:T240C
  • seg2:T300A
  • seg2:T330C
  • seg2:C342T
  • seg2:T384C
  • seg2:A405G
  • seg2:G441A
  • seg2:G447A
  • seg2:G510A
  • seg2:C513T
  • seg2:A576G
  • seg2:A594G
  • seg2:A705G

    • seg3

  • seg3:T88C
  • seg3:T111C
  • seg3:C117T
  • seg3:T339C
  • seg3:G414A
  • seg3:T423C
  • seg3:G549A
  • seg3:A618G
  • seg3:T654C
  • seg3:A771G
  • seg3:C813T
  • seg3:T837C
  • seg3:G867A
  • seg3:C897T
  • seg3:C918T
  • seg3:A935G
  • seg3:G936A
  • seg3:A987G

    • seg4

  • seg4:C27T
  • seg4:G39A
  • seg4:C188T
  • seg4:C252A
  • seg4:C270T
  • seg4:C276A
  • seg4:G297A
  • seg4:G312T
  • seg4:A318G
  • seg4:A351G
  • seg4:C375T
  • seg4:C378T
  • seg4:A427G
  • seg4:A435G
  • seg4:C441T
  • seg4:T444C
  • seg4:T456C
  • seg4:G457A

    • seg5

  • seg5:C3T
  • seg5:T46C
  • seg5:A55G
  • seg5:T95G
  • seg5:A121G
  • seg5:C178T
  • seg5:G215A
  • seg5:A224G
  • seg5:G244A
  • seg5:T298C
  • seg5:C313T
  • seg5:G361A
  • seg5:A373G
  • seg5:C380T
  • seg5:A454G
  • seg5:A514G
  • seg5:C523T
  • seg5:C608T

    • seg6

  • seg6:T9C
  • seg6:C125A
  • seg6:T134C
  • seg6:T212C
  • seg6:T276C
  • seg6:A358G
  • seg6:C394T
  • seg6:C399T
  • seg6:A504G
  • seg6:C519T
  • seg6:C534T
  • seg6:A660C
  • seg6:T714A
  • seg6:C849T
  • seg6:T879C
  • seg6:T885G
  • seg6:G921T
  • seg6:A945G

    • seg7

  • seg7:C33T
  • seg7:C46T
  • seg7:A83G
  • seg7:T113C
  • seg7:T125A
  • seg7:G316A
  • seg7:A419G
  • seg7:G482A
  • seg7:G500T
  • seg7:G521A
  • seg7:G536A
  • seg7:A557C
  • seg7:A566G
  • seg7:C656T
  • seg7:A919G
  • seg7:A967G

    • seg8

  • seg8:G26A
  • seg8:A118G
  • seg8:T163C
  • seg8:G190A
  • seg8:T341C
  • seg8:A352C
  • seg8:T355C
  • seg8:G376A
  • seg8:T391C
  • seg8:C419T
  • seg8:C487T
  • seg8:C604T
  • seg8:A610T
  • seg8:C632T
  • seg8:G661A
  • seg8:T775C
  • seg8:C882T
  • seg8:A950G
  • seg8:T963C
    • Deletions
    seg4:562-570
    Insertions
    ins_seg1:0:CTTTA, ins_seg1:2334:G, ins_seg2:0:GTTTTC, ins_seg2:2358:AAT, ins_seg3:0:GTTTGATTTATCACA, ins_seg3:2241:AGAAAC, ins_seg3:2245:ATCAAAAAT, ins_seg5:0:ATTTTCTTGTGAACTCCA, ins_seg5:1750:CGTTTGGAATATGGGTGTTTATTCTCATTAAAATAAATATAAAAAAT, ins_seg6:0:ATCTTCTCAAAACTGAAGCAAATAGTCCAAAAATGAACA, ins_seg6:1401:TGGGGGAGTGGTTAAGTCTGTTCTAAACCCTTTGTTCCTATTTTATTTGAACAATTATCCTTACTAAACTTAATTGTTT...

    Amino acid mutations

    Mutations called relative to the CY115157.1, CY115158.1, CY115156.1, KX058884.1, CY115154.1, CY073894.1, CY115152.1 & CY115155.1 references

    Substitutions

    HA1

  • HA1:T37I
  • HA1:I117V
  • HA1:A127T
  • HA1:E128D
  • HA1:K136E
  • HA1:P144L
  • HA1:N150K
  • HA1:G184E
  • HA1:N197E
  • HA1:K203R
  • HA1:R279K

    • M1

  • M1:T15I
  • M1:R105K

    • NA

  • NA:P42Q
  • NA:I45T
  • NA:V71A
  • NA:I120V
  • NA:K220N
  • NA:S295R
  • NA:N340D
  • NA:K343E
  • NA:E358K
  • NA:D384G
  • NA:A395V
  • NA:S397N
  • NA:V401I
  • NA:K404R

    • NEP

  • NEP:L30S
  • NEP:S93P

    • NP

  • NP:I9M
  • NP:S23A
  • NP:G63R
  • NP:T66A
  • NP:V453A

    • NS1

  • NS1:Y104H
  • NS1:K107N
  • NS1:L130F
  • NS1:H201Y

    • PA

  • PA:K312R
  • PA:T352A
  • PA:S530T
  • PA:I617V
  • PA:F709I
  • PA:N714S
  • PA:I723V

    • PB1

  • PB1:M65I
  • PB1:V474I

    • PB2

  • PB2:X303I
  • PB2:I492T
  • PB2:X582E
    • Deletions
    HA1:162-164
    Insertions
    None