GS_00G4AAE.2

USA/GS_00G4AAE.2/2025-08-05
Direct Submission

Center for Research on Influenza Pathogenesis (CRIP), CEIRS Data Processing and Coordinating Center

Submission details

Submission ID
PX399868.1.seg1/PX468491.1.seg2/PX399866.1.seg3/PX399865.1.seg4/PX399870.1.seg5/PX399871.1.seg6/PX399867.1.seg7/PX399869.1.seg8
Submitting group
Date submitted
2025-11-27 16:45:45 UTC
Date released
2025-11-27 16:51:55 UTC

INSDC

bioprojectAccession
INSDC accession seg1
INSDC accession seg2
INSDC accession seg3
INSDC accession seg4
INSDC accession seg5
INSDC accession seg6
INSDC accession seg7
INSDC accession seg8
NCBI release date
2025-09-22

Clade

Clade HA
D.1
Clade NA
C.5.3

Sample details

Collection country
USA
Collection date
2025-08-05
Isolate name
A/New York City/PX22899/2025

Host

Host

INSDC seg4

subtype_seg4
H1

INSDC seg6

subtype_seg6
N1

Alignment and QC

Length seg1
2341 (100%)
Total inserted nucs seg1
61
Total SNPs seg1
94
Length seg2
2341 (100%)
Total inserted nucs seg2
67
Total SNPs seg2
74
Length seg3
2233 (100%)
Total inserted nucs seg3
82
Total SNPs seg3
76
Length seg4
1777 (100%)
Total inserted nucs seg4
25
Total SNPs seg4
111
Length seg5
1565 (100%)
Total inserted nucs seg5
68
Total SNPs seg5
59
Length seg6
1458 (100%)
Total inserted nucs seg6
25
Total SNPs seg6
25
Length seg7
1027 (100%)
Total inserted nucs seg7
45
Total SNPs seg7
27
Length seg8
890 (100%)
Total inserted nucs seg8
27
Total SNPs seg8
37

Nucleotide mutations

Mutations called relative to the NC_026438.1, NC_026435.1, NC_026437.1, CY121680.1, NC_026436.1, MW626056.1, NC_026431.1 & NC_026432.1 references

Substitutions

seg1

  • A18G
  • G21A
  • C87A
  • A90C
  • A108G
  • C129A
  • A132G
  • G161A
  • A174G
  • G198A
  • T201C
  • C242T
  • C285A
  • C309T
  • C405T
  • G471A
  • A477G
  • G583A

seg2

  • G42A
  • C123T
  • A153G
  • A159G
  • G168A
  • C170A
  • G180A
  • C192T
  • T210C
  • T222C
  • G225A
  • C297T
  • G312A
  • A366G
  • C447T
  • T450C
  • A453G
  • G461A

seg3

  • R53A
  • T81C
  • G84C
  • A88G
  • C90T
  • C99T
  • A114T
  • C153T
  • C162T
  • C165T
  • G187A
  • G204A
  • G298A
  • A417G
  • G498A
  • G504A
  • G597A
  • A612G

seg4

  • C42A
  • A47G
  • G57A
  • A119G
  • C155T
  • T161C
  • C164T
  • G188A
  • G205A
  • A231C
  • C255T
  • G257A
  • C293A
  • C318T
  • G322A
  • G327A
  • G360A
  • G380A

seg5

  • G42T
  • C87T
  • G111A
  • C141A
  • C171T
  • T177C
  • C180T
  • C249A
  • A288C
  • G298A
  • G309A
  • T314C
  • G315A
  • R341A
  • T365A
  • A390G
  • T402C
  • A406C

seg6

  • T158C
  • T173C
  • G238T
  • G419A
  • G425A
  • C452A
  • C571A
  • C599A
  • G607A
  • A797G
  • A798G
  • A818G
  • C893T
  • G914T
  • A1049G
  • A1091G
  • A1177G
  • C1187T

seg7

  • G75A
  • C124A
  • G238A
  • G258A
  • A293G
  • G306A
  • G339A
  • G342A
  • C375A
  • G414A
  • T432C
  • G441T
  • G492A
  • C507A
  • A574G
  • G612A
  • C622A
  • G660A

seg8

  • C6A
  • C42T
  • C54T
  • T99C
  • C108A
  • T159C
  • G163A
  • C192T
  • C204T
  • A238G
  • G250A
  • C264T
  • C268A
  • C285T
  • C315T
  • A331G
  • A333T
  • A367G
Deletions
N/A
Insertions

seg1

ins_0:AGCAAAAGCAGGTCAAATATATTCAAT, ins_2280:TGTCGAATTGTTTAAAAACGACCTTGTTTCTACT

seg2

ins_0:AGCAAAAGCAGGCAAACCATTTGA, ins_2274:TGAATTTAACTTATCCTTCATGAAAAAATGCCTTGTTTCTACT

seg3

ins_0:AGCAAAAGCAGGTACTGATCCAAA, ins_2151:TTGTGGCAATGCTACTATTTGCTATCCATATTGTCCAAAAAAGTACCTTGTTTCTACT

seg4

ins_0:AGCAAAAGCAGG, ins_1752:CCTTGTTTCTACT

seg5

ins_0:AGCAAAAGCAGGGTAGATAATCACTCAATGAGTGACATCGAAGCC, ins_1497:AGAAAAATACCCTTGTTTCTACT

seg6

ins_0:AGCAAAAGCAGG, ins_1433:CCTTGTTTCTACT

seg7

ins_0:AGCAAAAGCAGGTAGATGTTTAAAG, ins_982:AAAACTACCTTGTTTCTACT

seg8

ins_0:AGCAAAAGCAGGGTGACAAAAACATA, ins_863:T

Amino acid substitutions

Substitutions called relative to the NC_026438.1, NC_026435.1, NC_026437.1, CY121680.1, NC_026436.1, MW626056.1, NC_026431.1 & NC_026432.1 references

Substitutions

HA1

  • HA1:R45K
  • HA1:K54Q
  • HA1:S74R
  • HA1:P83S
  • HA1:S84N
  • HA1:D86N
  • HA1:D97N
  • HA1:N129D
  • HA1:K130N
  • HA1:P137S
  • HA1:K142R
  • HA1:N156K
  • HA1:S157M
  • HA1:L161I
  • HA1:S162N
  • HA1:K163Q
  • HA1:S164T
  • HA1:S183P

HA2

  • HA2:L2I
  • HA2:E29D
  • HA2:E47K
  • HA2:I91V
  • HA2:S124H
  • HA2:E172K
  • HA2:E179D

M1

  • M1:L42I
  • M1:V80I
  • M1:K98R
  • M1:M192V
  • M1:Q208K
  • M1:K230R

M2

  • M2:D21G
  • M2:S23N

NA

  • NA:R77I
  • NA:T188N
  • NA:S200N
  • NA:I263M
  • NA:I264V
  • NA:K390R
  • NA:D451E
  • NA:V453M
  • NA:K469N

NEP

  • NEP:D2E
  • NEP:N29S
  • NEP:T48A
  • NEP:M83I

NP

  • NP:E14D
  • NP:V100I
  • NP:M105T
  • NP:X114E
  • NP:L122Q
  • NP:I136L
  • NP:V217I
  • NP:A251V
  • NP:V425I
  • NP:S498N

NS1

  • NS1:D2E
  • NS1:E55K
  • NS1:T80A
  • NS1:V84I
  • NS1:L90I
  • NS1:I111V
  • NS1:I123V
  • NS1:E125D
  • NS1:K131E
  • NS1:A155T
  • NS1:N205S
  • NS1:S213P

PA

  • PA:X18E
  • PA:I30V
  • PA:V63I
  • PA:V100I
  • PA:P224S
  • PA:S225C
  • PA:C241Y
  • PA:R262K
  • PA:N321K
  • PA:I330V
  • PA:A337T
  • PA:R362K
  • PA:I438V
  • PA:I505V

PA-X

  • PA-X:X18E
  • PA-X:I30V
  • PA-X:V63I
  • PA-X:V100I
  • PA-X:R199K
  • PA-X:N204S
  • PA-X:R206K
  • PA-X:R221Q
  • PA-X:A225V
  • PA-X:L229S

PB1

  • PB1:T57K
  • PB1:G154D
  • PB1:V200I
  • PB1:M372I
  • PB1:K386R
  • PB1:I397M
  • PB1:I435T
  • PB1:A643S
  • PB1:L753I

PB2

  • PB2:R54K
  • PB2:M66I
  • PB2:T81I
  • PB2:D195N
  • PB2:G225S
  • PB2:V292M
  • PB2:R293K
  • PB2:R299K
  • PB2:V344M
  • PB2:I354L
  • PB2:S453T
  • PB2:K526R
  • PB2:T588I
  • PB2:V667I
  • PB2:N715K
  • PB2:V731I

SigPep

  • SigPep:L8M
  • SigPep:A13T
Deletions
N/A
Insertions
N/A